摘要 |
<p>This invention provides compounds of formula (I) or its pharmacologically acceptable salt or solvate, wherein A represents aryl or a monocyclic or bicyclic heterocyclic group, R 1 represents a halide, nitro, substituted C 1-6 alkyl, optionally substituted amino, C 1-6 alkyloxycarbonyl, optionally substituted aryl, a heterocyclic group, or heterocyclic carbonyl, R 2 represents a hydrogen atom or C 1-6 alkyl, R 3 represents C 1-6 alkyl, all of R 4 , R 5 , and R 6 represent a hydrogen atom, R 7 represents C 1-6 alkyl, m is 1 or 2, and n is 1. The compounds are novel lincomycin derivatives having a potent activity against resistant pneumococci. The compounds can be used as an antimicrobial agent and are useful for preventing or treating bacterial infectious diseases.</p> |
申请人 |
MEIJI SEIKA KAISHA, LTD. |
发明人 |
UMEMURA, EIJIROU;WAKIYAMA, YOSHINARI;UEDA, KAZUTAKA;KUMURA, KOU;MASAKI, SATOMI;WATANABE, TAKASHI;YAMAMOTO, MIKIO;KAJI, CHIZUKO;AJITO, KEIICHI |