摘要 |
A sensor platform for use in sample analysis comprises a substrate (30) of refractive index m and a thin, optically transparent layer (32) of refractive index (n2) on the substrate, where n2 is greater than n1. The platform includes one of more sensing areas each for one or more capture elements. The platform also includes an immersion fluid with a refractive index n3 greater than an aqueous buffer but less than n2 to enhance the fluorescent signal of an affinity reaction. Also disclosed are an apparatus incorporating the platform and a method of using the platform. |