发明名称 TOPICAL ADMINISTRATION OF CATECHOLAMINES AND RELATED COMPOUNDS TO SUBCUTANEOUS MUSCLE TISSUE USING PERCUTANEOUS PENETRATION ENHANCERS
摘要 Compositions for the topical treatment of sagging subcutaenous muscle and overlying cutaneous tissue contain an active ingredient exhibiting or producing catecholamine activity such as catecholamines and/or related compounds in a dermatologically acceptable carrier that contains at least one percutaneous penetration enhancer. Examplary catecholamines include adrenaline, norepinepherine, dopamine and their precursors; catecholamine precursors such as tyrosine and phenylalanine are preferred. Many embodiments, particularly those employing tyrosine and/or phenylalanine as a catecholamine precursor, furthe r contain a neurotransmitter synthesis enhancer such as dimethylaminoethanol, and other co-factors such as vitamin B6 and pantotheni c acid or calcium pantothenate are included in the composition to enhance the action of the active ingredients. Other compounds that scaven ge free radicals and antioxidants may also be added.
申请公布号 CA2287477(C) 申请公布日期 2008.09.16
申请号 CA19982287477 申请日期 1998.05.04
申请人 PERRICONE, NICHOLAS V. 发明人 PERRICONE, NICHOLAS V.
分类号 A61K8/00;A61K8/44;A61K8/30;A61K8/31;A61K8/34;A61K8/36;A61K8/37;A61K8/40;A61K8/41;A61K8/42;A61K8/46;A61K8/49;A61K8/67;A61K8/73;A61K31/131;A61K31/137;A61K31/14;A61K31/198;A61K31/216;A61K31/221;A61K31/4045;A61K45/06;A61K45/08;A61P17/00;A61Q19/00;A61Q19/08 主分类号 A61K8/00
代理机构 代理人
主权项
地址