| 发明名称 |
INTRACELLULAR ISOFORM OF THE INTERLEUKIN-1-RECEPTOR ANTAGONIST |
| 摘要 |
It is described a new interleukin-1 antagonist active both against IL-1a and IL-1B, a new DNA sequence encoding the IL-1 antagonist and the method for obtaining a IL-1 antagonist by the recombinant DNA technique; it is also described the prophylactic, therapeutic and diagnostic use of such new IL-1 antagonist in pathologies deriving from the IL- 1 production.
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| 申请公布号 |
CA2202470(C) |
申请公布日期 |
2008.09.16 |
| 申请号 |
CA19952202470 |
申请日期 |
1995.10.12 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
COLOTTA, FRANCESCO;MUZIO, MARTA;MANTOVANI, ALBERTO |
| 分类号 |
C12N15/09;C12N15/25;A61K38/00;A61K38/20;A61P7/06;A61P29/00;A61P31/04;A61P35/02;A61P37/00;A61P37/06;C07K5/083;C07K14/54;C07K14/545;C12N5/10;C12N15/12;C12N15/24;C12N15/63;C12N15/85;C12P21/02 |
主分类号 |
C12N15/09 |
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