| 发明名称 |
Nucleic acids for inhibiting hairless protein expression and methods of use thereof |
| 摘要 |
The present invention provides DNAzymes and ribozymes that specifically cleave Hairless Protein mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of Hairless Protein mRNA. The invention also provides various methods of inhibiting the expression of Hairless Protein. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes and antisense oligonucleotides as active ingredients.
|
| 申请公布号 |
US7423022(B2) |
申请公布日期 |
2008.09.09 |
| 申请号 |
US20020122013 |
申请日期 |
2002.04.12 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
CHRISTIANO ANGELA M. |
| 分类号 |
A01K67/027;A61K31/70;A01N43/04;A61K9/127;A61K31/7088;A61K38/00;A61K47/10;A61K48/00;A61P17/14;C07H21/02;C07H21/04;C12N9/00;C12N15/09;C12N15/113 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
