发明名称 |
POLYMERS WITH CONTROLLED PHYSICAL STATE AND BIOERODIBILITY |
摘要 |
The present invention relates to polymers useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents. The polymers are prepared in such a manner that the rate and degree to which they are hydrolyzed can be controlled without addition of exogeneous acid. This discovery resides in th e incorporation of esters of short-chain .alpha.-hydroxy acids such as esters of glycolic acid, lactic acid or glycolic-co-lactic acid copolymer into the polymer chain and variation of the amount of these esters relative to the polymer as a whole.
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申请公布号 |
CA2242631(C) |
申请公布日期 |
2008.09.09 |
申请号 |
CA19972242631 |
申请日期 |
1997.01.03 |
申请人 |
ADVANCED POLYMER SYSTEMS, INC. |
发明人 |
HELLER, JORGE;NG, STEVE Y. |
分类号 |
A61K47/34;C08G65/28;A61K9/20;A61K9/22;A61L27/00;A61L27/18;C08G63/664;C08G65/00;C08G65/34 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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