PHARMACEUTICAL AEROSOL COMPOSITION

摘要

A composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane and a cosolvent. The composition further includes a low volatility component which is added t o increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler. With the addition of t he low volatility component, the MMAD of the aerosol particles may be comparable to the MMAD of aerosol particles of an aerosol inhaler including CFC as propellant.