SULFONAMIDE DERIVATIVE

摘要

Disclosed is a compound represented by the formula (1) below having a strong Rho kinase inhibitory activity, a salt thereof or a derivative of any of them as a prodrug. (In the formula (1) below, A represents a nitrogen-containing saturated ring; m represents a number of 0-2; n represents a number of 1-4; G¹ represents a hydrogen atom, a chlorine atom, a hydroxy group, an alkoxy group or an amino group; G² represents a halogen atom, a hydroxy group, a cyano group, a carboxy group, an alkyl group, an alkenyl group or the like; G³ represents a hydrogen atom, a halogen atom, a hydroxy group, a cyano group, a carboxy group, an alkyl group, an alkenyl group or the like; Y represents a single bond or -C(R3)(R4)- (wherein R3 and R4 represent a hydrogen atom or alkyl group, or alternatively they combine together to form a saturated hydrocarbon ring group); G⁴ represents a hydroxy group (provided that Y is a single bond) or -N(R1)(R2) (wherein R1 and R2 represent a hydrogen atom, an alkyl group, an aralkyl group, an alkenyl group or the like; and G⁵ represents a substituent at a carbon atom constituting the ring A, which is specifically a hydrogen atom, a fluorine atom or an alkyl group.)