SUSTAINED RELEASE PARENTERAL FORMULATIONS OF BUPRENORPHINE
摘要
An oil-in-water buprenorphine formulation including buprenorphine and a surfactant that emulsifies the buprenorphine in oil, wherein the drug release is controlled by varying the oil concentration and/or pH. A buprenorphine aqueous suspension formulation including a free base buprenorphine and a suspension stabilizer. A buprenorphine oil formulation including a buprenorphine salt suspended in a pharmaceutically acceptable oil. Methods of providing sustained release of buprenorphine over a period of time.
申请公布号
WO2008106571(A2)
申请公布日期
2008.09.04
申请号
WO2008US55211
申请日期
2008.02.28
申请人
ABBOTT LABORATORIES;LUANGDILOK, CARMELA;FLANAGAN, DOUGLAS R.;LI, LUK-CHIU;WIDMAN, MATTHEW
发明人
LUANGDILOK, CARMELA;FLANAGAN, DOUGLAS R.;LI, LUK-CHIU;WIDMAN, MATTHEW