| 发明名称 |
INDOLE AND INDOLINE CYCLOPROPYL AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS |
| 摘要 |
The invention is directed to indole and indoline cyclopropyl amide deriva tives as EP4 receptor antagonists useful for the treatment of EP4 mediated d iseases or conditions, such as acute and chronic pain, osteoarthritis, rheum atoid arthritis and cancer. Pharmaceutical compositions and methods of use a re also included.
|
| 申请公布号 |
CA2679175(A1) |
申请公布日期 |
2008.09.04 |
| 申请号 |
CA20082679175 |
申请日期 |
2008.02.22 |
| 申请人 |
MERCK FROSST CANADA LTD. |
发明人 |
HAN, YONGXIN;BOYD, MICHAEL;COLUCCI, JOHN |
| 分类号 |
C07D209/08;A61K31/404;A61K31/41;C07D403/12 |
主分类号 |
C07D209/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
