| 摘要 |
Disclosed are genes and proteins related to the biosynthesis and function of mono-methyl branched-chain fatty acids (mmBCFA) in eukaryotes, as well as the functions of mmBCFA in eukaryotic organisms. Also disclosed are methods to regulate the biosynthesis and function of mmBCFA in an organism, methods to use the valuable targets associated with mmBCFA biosynthesis and function as therapeutic agents and to screen for pharmaceuticals and nutraceuticals, or to investigate or screen for regulators of metabolism, growth, development, and reproduction in eukaryotes. The present invention also includes highly specific and useful animal models for mmBCFA biosynthesis and function that can be used to explore pharmaceutical applications of the mmBCFA-involved biological processes.
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