| 发明名称 |
A process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide |
| 摘要 |
<p>A process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz/b,f/azepine-5-carboxamide (2) from 10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (1), comprising oxidising 10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (1) by reaction with peroxyacetic acid in the presence of a metal catalyst in a substantially inert solvent.
<Chemistry id="chema01" num="0001"><Image id="ia01" he="46" wi="75" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></p> |
| 申请公布号 |
EP1958938(A3) |
申请公布日期 |
2008.09.03 |
| 申请号 |
EP20080075527 |
申请日期 |
2002.05.22 |
| 申请人 |
BIAL - PORTELA & CA., S.A. |
发明人 |
LEARMONTH, DAVID ALEXANDER |
| 分类号 |
C07D491/04;C07D223/22;A61P25/08;C07B61/00;C07D491/044 |
主分类号 |
C07D491/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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