发明名称 |
COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLTL ANTAGONIST FOR TREATING CANCER |
摘要 |
The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists. |
申请公布号 |
EP1962903(A1) |
申请公布日期 |
2008.09.03 |
申请号 |
EP20060820476 |
申请日期 |
2006.12.12 |
申请人 |
ASTRAZENECA AB |
发明人 |
BROWN, JEFFREY, LESTER;EMERY, STEPHEN, CHARLES;BLAKEY, DAVID, CHARLES |
分类号 |
C07K16/22;A61K45/06 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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