发明名称 |
INSTALLATION OF GENOMES OR PARTIAL GENOMES INTO CELLS OR CELL-LIKE SYSTEMS |
摘要 |
A method is provided for introducing a genome into a cell or cell-like system. The introduced genome may occur in nature, be manmade with or without automation, or may be a hybrid of naturally occurring and manmade materials. The genome is obtained outside of a cell with minimal damage. Materials such as a proteins, RNAs, polycations, nucleoid condensation proteins, or gene translation systems may accompany the genome. The genome is installed into a naturally occurring cell or into a manmade cell-like system. A cell-like system or synthetic cell resulting from the practice of the provided method may be designed and used to yield gene-expression products, such as desired proteins. By enabling the synthesis of cells or cell-like systems comprising a wide variety of genomes, accompanying materials and membrane types, the provided method makes possible a broader field of experimentation and bioengineering than has been available using prior art methods. |
申请公布号 |
EP1963515(A2) |
申请公布日期 |
2008.09.03 |
申请号 |
EP20060851502 |
申请日期 |
2006.12.22 |
申请人 |
J. CRAIG VENTER INSTITUTE, INC. |
发明人 |
GLASS, JOHN I.;YOUNG, LEI;LARTIGUE, CAROLE;ASSAD-GARCIA, NACYRA;SMITH, HAMILTON O.;HUTCHISON, CLYDE;VENTER, J. CRAIG |
分类号 |
C12P19/34;C07H21/00;C07H21/04;C12N1/00;C12N1/20;C12N5/02;C12N5/04;C12N15/64 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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