发明名称 |
TRIAZOLYL TROPANE DERIVATIVES AS CCR5 MODULATORS |
摘要 |
<p>The present invention provides compounds of the formula:
wherein R 1 is C 3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C 1-6 alkyl optionally substituted by one or more fluorine atoms, or C 3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and
R 2 is phenyl optionally substituted by one or more fluorine atoms,
and pharmaceutically acceptable salts and solvates thereof; in combination with one or more additional therapeutic agents.</p> |
申请公布号 |
EP1526134(B1) |
申请公布日期 |
2008.09.03 |
申请号 |
EP20040004193 |
申请日期 |
2001.05.09 |
申请人 |
PFIZER LIMITED;PFIZER INC. |
发明人 |
PERROS, MANOUSSOS;PRICE, DAVID ANTHONY;STAMMEN, BLANDA LUZIA CHRISTA;WOOD, ANTHONY |
分类号 |
C07D451/04;A61K31/4196;A61K31/46;A61P1/04;A61P1/12;A61P1/18;A61P3/10;A61P9/04;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P15/00;A61P25/00;A61P25/28;A61P27/16;A61P29/00;A61P31/18;A61P37/00;A61P37/06;A61P43/00;C07B53/00;C07B61/00;C07C233/60;C07C233/61;C07C233/63;C07D |
主分类号 |
C07D451/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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