发明名称 |
Process for preparing optically active 2,3-dihydrobenzofuran compounds |
摘要 |
A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound: [wherein R<SUP>1 </SUP>and R<SUP>2 </SUP>are each hydrogen or an optionally substituted hydrocarbon group; R<SUP>3 </SUP>is an optionally substituted aromatic group; and C is a benzene ring which may further have a substituent in addition to the amino group]. The process enables industrially advantageous production of intermediates for the synthesis of optically active 2,3-dihydrobenzofuran compounds useful as preventive and/or therapeutic drugs for neurodegenerative diseases and so on.
|
申请公布号 |
US7420070(B2) |
申请公布日期 |
2008.09.02 |
申请号 |
US20050054371 |
申请日期 |
2005.02.09 |
申请人 |
TAKODA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
AOKI ISAO;ADACHI MARI;TAWADA HIROYUKI;YAMASHITA MAKOTO;SERA MISAYO |
分类号 |
C07D405/00;C07D307/00;C07D307/79;C07D405/04;C07F9/6574 |
主分类号 |
C07D405/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|