SYNERGISTIC COMBINATION OF PDE INHIBITORS AND ADENYLATE CYCLASE AGONISTS OR GUANYL CYCLYSE AGONISTS

摘要

A diseased state based on acute or chronic obstruction of vessels and/or bronchi, acute or chronic inflammation and/or edema formation is advantageously treated by the combined administration of a PDE inhibitor with either an adenylate cyclase agonist or a guanylate cyclase agonist to a subject in need of such therapy. Administration can be either concurrent or in either order.