发明名称 |
AEROSOL SOLUTION FORMULATIONS, PRESSURIZED METERED DOSE INHALERS AND METHOD FOR FILLING THEREOF |
摘要 |
Aerosol solution formulations for use in an aerosol inhaler which comprise 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone or a salt thereof, in particular the hydrochloride salt (TA 2005), as an active ingredient, a propellant containing a hydrofluoroalkane, and a cosolvent, stabilized by addition of a specific small amount of a high concentrated phosphoric acid and optionally by the use of a suitable can having part or all of its internal metallic surfaces lined with an inert organic coating. |
申请公布号 |
EA010311(B1) |
申请公布日期 |
2008.08.29 |
申请号 |
EA20060001578 |
申请日期 |
2005.02.25 |
申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
LEWIS DAVID;GANDERTON DAVID;MEAKIN BRIAN;DELCANALE MAURIZIO;PIVETTI FAUSTO |
分类号 |
A61K9/12;A61K9/00;A61K31/47;A61K31/4704;A61L9/04;A61M15/00;B65D83/14 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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