发明名称 |
Monoclonal antibodies against extracellular loops of C5aR |
摘要 |
Disclosed is an antibody that is reactive with an extracellular loop(s) of C5aR other than the N-terminal domain and which reduces or inhibits the binding of C5a to C5aR, with the proviso that the antibody reduces binding of C5a to C5aR by at least 20% when compared with the binding of C5a to C5aR in the absence of the antibody.
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申请公布号 |
NZ534399(A) |
申请公布日期 |
2008.08.29 |
申请号 |
NZ20030534399 |
申请日期 |
2003.01.24 |
申请人 |
G2 THERAPIES LTD |
发明人 |
MACKAY, CHARLES REAY |
分类号 |
G01N33/48;A61K38/00;A61K39/00;A61K39/104;A61K39/395;A61K48/00;A61K49/00;A61K49/04;A61K51/00;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K16/28;C12N5/10;C12N5/20;C12N15/09;C12P21/08;G01N33/53;(IPC1-7):C07K16/28 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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