发明名称 |
ИНДУКЦИЯ АПОПТОЗА В ОПУХОЛЕВЫХ КЛЕТКАХ, ЭКСПРЕССИРУЮЩИХ TOLL-ПОДОБНЫЙ РЕЦЕПТОР |
摘要 |
Some types of cancer cells express one or more Toll-like receptors (TLRs). These TLRs are therapeutic targets. The invention relates to methods for treating Toll-like receptor expressing cancers and tumor cells by selecting a TLR expressing tumor cell and contacting the cell with a therapeutically effective amount of a TLR ligand. The invention particularly relates to methods for treating TLR3 expressing cancers and tumor cells using TLR3 agonists. |
申请公布号 |
RU2007105987(A) |
申请公布日期 |
2008.08.27 |
申请号 |
RU20070105987 |
申请日期 |
2005.07.19 |
申请人 |
ШЕРИНГ КОРПОРЕЙШН (US) |
发明人 |
ЛЕБЕК Серж (FR);РЕННО Туфик (FR);САЛОН Брюно (CH);КОСТ-ИНВЕРНИЦЦИ Изабель (FR);РИССОАН Мари-Клотильд (FR) |
分类号 |
A61K45/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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