发明名称 THIOXANTHINE DERIVATIVES AND THEIR USE AS INHIBITORS OF MPO.
摘要 <p>There are disclosed novel compounds of Formula (I) wherein L, R1, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardio- and cerebrovascular atherosclerotic disorders and peripheral artery disease and respiratory disorders.</p>
申请公布号 MX2008013033(A) 申请公布日期 2008.10.17
申请号 MX20080013033 申请日期 2007.04.12
申请人 ASTRAZENECA AB 发明人 ANNA-KARIN TIDEN;JENNY VIKLUND
分类号 C07D473/22;H01L31/04;A61K31/52;A61K31/522;A61P9/10;A61P11/08;A61P25/16;C07D473/20;H01R4/00;H01R4/16 主分类号 C07D473/22
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