发明名称 Biologically active conjugate of a biopolymer and therapeutic agent
摘要 A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved in vivo stability and activity, and can be targeted to a variety of cells, tissues and organs.
申请公布号 US7417021(B2) 申请公布日期 2008.08.26
申请号 US20040841081 申请日期 2004.05.07
申请人 GENZYME CORPORATION 发明人 CALIAS PERICLES;MILLER ROBERT J.
分类号 A61K38/00;A61K9/00;A61K38/46;A61K47/48;C07K17/02;C12N11/02 主分类号 A61K38/00
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