| 发明名称 |
POLYKETIDE SYNTHASE ENZYMES AND RECOMBINANT DNA CONSTRUCTS THEREFOR |
| 摘要 |
Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products. |
| 申请公布号 |
CA2343880(C) |
申请公布日期 |
2008.08.26 |
| 申请号 |
CA19992343880 |
申请日期 |
1999.10.01 |
| 申请人 |
KOSAN BIOSCIENCES, INC. |
发明人 |
KHOSLA, CHAITAN;SANTI, DANIEL;CHU, DANIEL;REEVES, CHRISTOPHER;WU, KAI |
| 分类号 |
C07D498/18;C12N15/09;A61K31/436;A61P25/00;A61P37/06;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/10;C12N9/12;C12N15/52;C12P17/18;C12P19/32;C12P19/62 |
主分类号 |
C07D498/18 |
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