发明名称 Antisense oligonucleotides capable of inhibiting the formation of capillary tubes by endothelial cells
摘要 A pharmaceutical composition that blocks angiogenesis comprising as active agent at least one substance selected from the group consisting of (i) a nucleic acid molecule of a gene coding for protein IRS-1, a complementary sequence or a fragment thereof and (ii) a molecule which inhibits expression of a nucleic acid molecule according to (i).
申请公布号 US7417033(B2) 申请公布日期 2008.08.26
申请号 US20030735512 申请日期 2003.12.12
申请人 GENE SIGNAL INTERNATIONAL 发明人 AL-MAHMOOD SALMAN
分类号 A61K31/70;C12N15/09;A61K9/08;A61K31/7088;A61K38/00;A61K45/00;A61K48/00;A61P1/04;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P15/00;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P29/00;A61P35/00;C07H21/02;C07H21/04;C12N15/113;C12Q1/68 主分类号 A61K31/70
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