发明名称 |
STIMULATORY AUTO-ANTIBODIES TO THE PDGF RECEPTOR AS PATHOLOGY MARKER AND THERAPEUTIC TARGET |
摘要 |
An in vitro method for detecting the presence in a body sample of auto-antibodies for the PDGF receptor suitable for the diagnosis and prognosis of autoimmune diseases, in particular the systemic sclero-is and related diagnostic kits. Use of an inhibitor of ROS and/or Ras-ERK1/2 for the preparation of a medicament for therapeutic treatment of autoimmune diseases or of treating the Graft-Versus-Host-Reaction (GVHR). Pharmaceutical composition comprising an effective amount of an inhibitor of ROS and/or Ras-ERK1/2, and proper diluents, and /or excipients, and/or adjuvants.
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申请公布号 |
KR20080077347(A) |
申请公布日期 |
2008.08.22 |
申请号 |
KR20087002211 |
申请日期 |
2008.01.28 |
申请人 |
AVVEDIMENTO VITTORIO ENRICO;SVEGLIATI BARONI SILVIA;SANTILLO MARIAROSA;FUNARO ADA;LUCHETTI MICHELE;GABRIELLI ARMANDO |
发明人 |
AVVEDIMENTO VITTORIO ENRICO;ARMANDO GABRIELLI;SANTILLO MARIAROSA;FUNARO ADA;LUCHETTI MICHELE;SVEGLIATI BARONI SILVIA |
分类号 |
G01N33/564;A61K38/18 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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地址 |
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