发明名称 |
Plant Activation of Insect Toxin |
摘要 |
Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
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申请公布号 |
US2008200415(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20070940002 |
申请日期 |
2007.11.14 |
申请人 |
PIONEER HI-BRED INTERNATIONAL, INC.;E.I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
ABAD ANDRE;FLANNAGAN RONALD D.;HERRMANN RAFAEL;LU ALBERT L.;MCCUTCHEN BILLY F.;PRESNAIL JAMES K.;RICE JANET A.;WONG JAMES F.;YU CAO-GUO |
分类号 |
A61K31/7088;A01H1/00;A01H5/00;A01P7/04;C07K14/325;C12N9/64;C12N15/32;C12N15/82 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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