发明名称 |
SALTS, PRODRUGS AND POLYMORPHS OF FAB I INHIBITORS |
摘要 |
Salts of compounds according to formula (I) wherein the X is selected from the group consisting of H<SUB>2</SUB>SO<SUB>4</SUB>, HSO<SUB>3</SUB>R', HSO<SUB>3</SUB>Ar, H<SUB>3</SUB>PO<SUB>4</SUB>, HCl, HBr, CF<SUB>3</SUB>CO<SUB>2</SUB>H and CCl<SUB>3</SUB>CO<SUB>2</SUB>H. The preferred salt being the p-toluene sulfonate. These compounds and their pharmaceutical composition are useful as Fabl inhibitors for treating bacterial infections. |
申请公布号 |
WO2008098374(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
WO2008CA00300 |
申请日期 |
2008.02.15 |
申请人 |
AFFINIUM PHARMACEUTICALS, INC.;PAULS, HENRY;RAMNAUTH, JAILALL |
发明人 |
PAULS, HENRY;RAMNAUTH, JAILALL |
分类号 |
C07D471/04;A61K31/4375;A61L2/16;A61P31/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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