<p>The present invention is related to complementarity determining region (CDR) -grafted humanized R24 antibodies that bind to the GD3 ganglioside antigen. The humanized antibodies disclosed herein have characteristics that are comparable or superior to the murine R24 antibody, and the humanized antibodies are useful in treating melanoma.</p>
申请公布号
WO2008101234(A2)
申请公布日期
2008.08.21
申请号
WO2008US54220
申请日期
2008.02.18
申请人
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;CHAPMAN, PAUL;DAVIDSON, LISA;SALDANHA, JOSE, W.
