The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.
申请公布号
WO2008100624(A2)
申请公布日期
2008.08.21
申请号
WO2008US02119
申请日期
2008.02.15
申请人
MERRIMACK PHARMACEUTICALS, INC.;SCHOEBERL, BIRGIT;NIELSEN, ULRIK;FELDHAUS, MICHAEL
发明人
SCHOEBERL, BIRGIT;NIELSEN, ULRIK;FELDHAUS, MICHAEL