发明名称 |
Methods and compositions for modulating BK channel activity and vasodilation |
摘要 |
Methods and compositions are provided for modulating myocyte BK channel activity and for screening for modulators of BK channel activity. The methods and compositions are useful in the treatment of disorders where increasing myocyte BK channel activity can attenuate, revert or prevent the disorder. For example, the methods and compositions are useful for treating disorders ameliorated by increasing vasodilation and blood flow in a subject, in particular, increasing cerebral blood flow.
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申请公布号 |
US2008200439(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20070005639 |
申请日期 |
2007.12.27 |
申请人 |
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
DOPICO ALEJANDRO M.;BUKIYA ANNA NODAROVNA;LIU JIANXI |
分类号 |
A61K31/575;A61P9/00;C12N9/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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