Methods for Treating Parkinson's Disease

摘要

Polypeptides and other compounds that can bind specifically to the C_H2-C_H3 cleft of an immunoglobulin molecule, and methods for using such polypeptides and compounds to inhibit Fc-mediated immune complex formation, immune complexed IgG binding to IgG FgammaR, and immune complexed IgG binding to mC1q (membrane C1q) or soluble C1q. The polypeptides and compounds provided herein can have therapeutic use in treating Parkinson's disease (PD).