| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a medicament for treating complication of true diabetes mellitus. <P>SOLUTION: This drug was prepared by fermentation of licorice followed by getting a lot of glycerizine using hydrochloric acid and not by boiling for fear of destruction of enzymes and flavonoids. The licorice prepared by fermentation is rich in amylase which improves diabetic complications due to increase of cellular enzymatic activity. Many diabetic complications such as nephropathy, peripheral neuritis, cataract and retinopathy have shown improvement with flavonoids present in licorice. It has been found that this effect is caused from the prevention of transformation of glucose to sorbitol by inhibiting aldose reductase enzyme, thus avoiding the accumulation of sorbitol in several tissues including lens, retina, kidney, blood vessels, peripheral nerves and striated muscles. <P>COPYRIGHT: (C)2008,JPO&INPIT |
