发明名称 |
Use Of Fumagillin And The Derivatives Thereof To Increase The Bioavilability Of The Macrocyclic Lactones |
摘要 |
The invention relates to the use of fumagillin and the analog derivatives thereof, as inhibitors of cellular transporters, such as ABC transporters, and especially of P-glycoprotein, in order to increase the bioavailability of active ingredients that can be used in the treatment of pathologies such as cancers or parasitic diseases, and especially in order to increase the bioavailability of the macrocyclic lactones.
|
申请公布号 |
US2008200402(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20060917031 |
申请日期 |
2006.06.08 |
申请人 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE |
发明人 |
ALVINERIE MICHEL;DUPUY JACQUES;LESPINE ANNE;SUTRA JEAN-FRANCOIS |
分类号 |
A61K31/336;A61K31/7048;A61P33/00;A61P35/00 |
主分类号 |
A61K31/336 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|