发明名称 |
NEW ANTIGEN DERIVED FROM HELICOBACTER PYLORI, ANTIGENIC COMPOSITION, AND DETECTION METHOD FOR HELICOBACTER PYLORI ANTIBODY |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide an antigenic composition containing the antigenic protein having high specificity to Helicobacter pylori antibody in the blood serum of Japanese or further of Asian. <P>SOLUTION: The antigenic composition including a part of CagA is a protein which is prepared by treating Helicobacter pylori with a buffer solution containing an alkylglycoside-based nonionic surfactant; feeding the solubilized extract to gel filtration chromatography; and concentrating and desalting the resultant polymer fraction. The protein is separated into three or more between 81 kDa and 125 kDa in the two-dimensional electrophoresis based on isoelectric point and molecular weight. <P>COPYRIGHT: (C)2008,JPO&INPIT |
申请公布号 |
JP2008189648(A) |
申请公布日期 |
2008.08.21 |
申请号 |
JP20070074807 |
申请日期 |
2007.03.22 |
申请人 |
TOYAMA UNIV |
发明人 |
SUGIYAMA TOSHIRO |
分类号 |
C07K14/195;G01N27/447;G01N30/88 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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