| 发明名称 |
CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S |
| 摘要 |
Carbon-linked tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
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| 申请公布号 |
US2008200454(A1) |
申请公布日期 |
2008.08.21 |
| 申请号 |
US20080031010 |
申请日期 |
2008.02.14 |
| 申请人 |
AMERIKS MICHAEL K;AXE FRANK U;EDWARDS JAMES P;GRICE CHERYL A;CAI HUI;GLEASON ELIZABETH ANN;MEDUNA STEVEN P;TAYS KEVIN L;WIENER JOHN J M;WICKBOLDT ALVAH T |
发明人 |
AMERIKS MICHAEL K.;AXE FRANK U.;EDWARDS JAMES P.;GRICE CHERYL A.;CAI HUI;GLEASON ELIZABETH ANN;MEDUNA STEVEN P.;TAYS KEVIN L.;WIENER JOHN J. M.;WICKBOLDT ALVAH T. |
| 分类号 |
A61K31/437;A61K31/496;A61K31/53;A61K31/541;A61K31/55;A61P1/00;A61P3/10;A61P11/00;A61P17/00;A61P25/00;A61P29/00;A61P35/00;A61P37/00;C07D471/04 |
主分类号 |
A61K31/437 |
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