发明名称 |
Methods for reduction of adipose tissue mass |
摘要 |
The present disclosure relates to diets, compounds, e.g., GCN2 agonists and methods that selectively reduce adipose tissue mass relative to the mass of other tissue types and increase insulin sensitivity. Another aspect of the disclosure relates to methods for identifying GCN2 agonists that will decrease the activity and/or expression of one or more of adipogenic genes thereby selectively inhibiting the cellular mechanisms that lead to fat production. Such agonists have the effect of reducing adipose tissue mass in an individual.
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申请公布号 |
US2008200422(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20070004518 |
申请日期 |
2007.12.21 |
申请人 |
CAVENER DOUGLAS R;GUO FEIFAN |
发明人 |
CAVENER DOUGLAS R.;GUO FEIFAN |
分类号 |
A61K31/70;A23K1/18;A61K31/135;A61K31/196;A61K31/351;A61K31/4164;A61P3/06;C12Q1/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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