METHOD FOR PREPARING AN IMPLANTABLE PROSTHESIS FROM A POROUS BASE BODY AND ASSOCIATED PROSTHESIS AND USE THEREOF

摘要

The invention relates to a method for preparing an implantable prosthesis from a porous base body and to the associated prosthesis and use thereof. The inventive method comprises the application (50) of a coating (14) to the body (12), said coating being intended to receive a bioactive agent comprising a cyclodextrin and/or a cyclodextrin derivative and/or a cyclodextrin inclusion complex or a poly(carboxylic) acid and a catalyst. The method includes a heating step (58) in which the body (12) is heated to a temperature of between 100°C and 220°C for between 1 and 90 minutes, followed by a step in which the body (12) is washed with water and dried. The method can also include an optional subsequent step in which the body is impregnated in a concentrated solution of at least one bioactive agent. After the drying step, a sealing coating is deposited on the body (12), after which the body (12) defines an internal sealed liquid flow channel.