发明名称 1,2-Dihydro-Spiro[3H-Indole-3,4'-Piperidine] Compounds, as Modulators of the Mas Receptor Novel
摘要 The present invention relates to certain 1,2-dihydro-spiro[3H-indole-3,4'-piperidine]compounds of Formula (Ia): and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein G, R1, R2, R3, R4, R5, and Ar are as disclosed herein ("Compound(s) of the Invention"), which are useful, for example, as cardio-protective and/or neuro-protective agents. The invention also provides pharmaceutical compositions comprising a Compound of the Invention and methods for treating, preventing and/or managing a vascular, cardiovascular or neurological disease or disorder, comprising administering to a patient in need thereof a Compound of the Invention.
申请公布号 US2008200491(A1) 申请公布日期 2008.08.21
申请号 US20060917731 申请日期 2006.06.21
申请人 TRAN THUY-ANH;HAN SANGDON;BOATMAN P DOUGLAS 发明人 TRAN THUY-ANH;HAN SANGDON;BOATMAN P. DOUGLAS
分类号 A61K31/438;A61P9/10;A61P25/02;A61P25/16;C07D471/10 主分类号 A61K31/438
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