INDOLEAMINE 2,3-DIOXYGENASE, PD-1/PD-L PATHWAYS, AND CTLA4 PATHWAYS IN THE ACTIVATION OF REGULATORY T CELLS
摘要
<p>The present invention includes methods of enhancing immune responses by administering an inhibitor of indoleamine-2,3-dioxygenase (IDO) along with one or more inhibitors of the PD-1/PD-L pathway and/or one or more inhibitors of the CTLA4 pathway.</p>
申请公布号
WO2008100562(A2)
申请公布日期
2008.08.21
申请号
WO2008US01946
申请日期
2008.02.14
申请人
MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC.;REGENTS OF THE UNIVERSITY OF MINNESOTA;SHARMA, MADHAV, D.;BLAZAR, BRUCE, R.;MELLOR, ANDREW, L.;MUNN, DAVID, H.
发明人
SHARMA, MADHAV, D.;BLAZAR, BRUCE, R.;MELLOR, ANDREW, L.;MUNN, DAVID, H.