| 摘要 |
PROBLEM TO BE SOLVED: To provide an early stage detection method as to a nephritis detection reagent for a kidney disease. SOLUTION: The present invention is constituted as follows. 1. A method and a reagent for detecting an anti-7s-autoantibody characteristic to a nephritis, using the 7s of a type IV collagenα3 chain,α4 chain,α5 chain and/orα6 chain of a main component in a glomerule basement membrane (GBM) as an antigen, and/or a peptide thereof (7s hereafter) as the antigen. 2. A method and a reagent for detecting the 7s characteristic to the nephritis, using an antibody reacting using the 7s of the type IV collagenα3 chain,α4 chain,α5 chain and/orα6 chain of the main component in the glomerule basement membrane (GBM) as the antigen, and/or a peptide thereof (7s hereafter) as the antigen. COPYRIGHT: (C)2008,JPO&INPIT
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