摘要 |
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A<SUP>1</SUP>, A<SUP>2</SUP>, A<SUP>3</SUP>, A<SUP>4</SUP>, A<SUP>5</SUP>, A<SUP>6</SUP>, A<SUP>7</SUP>, A<SUP>8</SUP>, X<SUP>4</SUP>, X<SUP>6</SUP>, R<SUP>2a</SUP>, R<SUP>x</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, and R<SUP>6 </SUP>are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
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