发明名称 |
Use of a polypeptide domain to modulate the tumorigenic and metastatic potential of cancer cells |
摘要 |
The present invention reates to the use of a polypeptide domain to modulate the tumorigenic and metastatic potential of cancer cells. More specifically, the present invention relates to a domain of a Secretory Leukocyte Protease Inhibitor (SLPI) to modulate tumor invasiveness and/or metastasis. It further relates to compounds, such as antibodies, that interact with the domain and repress the tumor invasiveness and/or the metastasis.
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申请公布号 |
US2008199472(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20080070239 |
申请日期 |
2008.02.14 |
申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW;VRIJE UNIVERSITEIT BRUSSEL |
发明人 |
REVETS HILDE;BAETSELIER PATRICK DE;DEVOOGDT NICK;GHASSABEH GHOLAMREZA HASSANZADEH |
分类号 |
A61K39/395;A61K38/00;A61K38/57;A61P35/00;A61P43/00;C12N5/06;C12Q1/68 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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