| 发明名称 | Fusion peptide designed to reduce plaque bacteria and yeast in the oral cavity | ||
| 摘要 | The present invention relates generally to dental diseases, caries and periodontal disease. More specifically, the invention relates to Lactoferrin and PAK fusion peptides (PAK-LF), along with therapeutic, diagnostic and research uses for these polypeptides. The present invention also provides methods of treating dental diseases, caries and periodontal disease. | ||
| 申请公布号 | US9408889(B2) | 申请公布日期 | 2016.08.09 |
| 申请号 | US201214113245 | 申请日期 | 2012.04.23 |
| 申请人 | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 发明人 | Fine Daniel H.;Velliyagounder Kabilan |
| 分类号 | A61K38/16;A61K45/06;C07K14/00;A23L1/305;C07K14/79;C07K14/21;A61K38/00 | 主分类号 | A61K38/16 |
| 代理机构 | Fox Rothschild LLP | 代理人 | Fox Rothschild LLP |
| 主权项 | 1. A composition for inhibiting bacterial growth in the oral cavity comprising a fusion peptide comprising: i. a lysine form of a Lactoferrin polypeptide; and ii. a PAK polypeptide, wherein the fusion peptide consists essentially of SEQ ID NO: 5. | ||
| 地址 | New Brunswick NJ US | ||