| 发明名称 |
COVALENT INHIBITORS OF KRAS G12C KRAS G12C |
| 摘要 |
Irreversible inhibitors of G12C mutant K-Ras protein are provided. Also disclosed are methods to modulate the activity of G12C mutant K-Ras protein and methods of treatment of disorders mediated by G12C mutant K-Ras protein. |
| 申请公布号 |
HK1215029(A1) |
申请公布日期 |
2016.08.12 |
| 申请号 |
HK20160103063 |
申请日期 |
2016.03.16 |
| 申请人 |
Araxes Pharma LLC |
发明人 |
Pingda REN;Yi LIU;Liansheng LI;Jun FENG;Tao WU |
| 分类号 |
C07D |
主分类号 |
C07D |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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