发明名称 |
Method for L-threonine production |
摘要 |
A method for producing L-threonine using a microorganism is provided. In the method, the threonine dehydratase (tdc) gene existing in the genomic DNA of the microorganism is partially deactivated using a recombination technique. For a microorganism strain with enhanced activity of threonine operon-containing enzymes and the phosphoenolpyruvate carboxylase (ppc) gene, the tdc gene engaged in one of the four threonine metabolic pathways is specifically deactivated, thereby markedly increasing the yield of L-threonine. |
申请公布号 |
EP1347057(B1) |
申请公布日期 |
2008.08.20 |
申请号 |
EP20020253703 |
申请日期 |
2002.05.27 |
申请人 |
CJ CHEILJEDANG CORPORATION |
发明人 |
PARK, JAE-YONG;KIM, DAE-CHEOL;LEE, BYOUNG-CHOON;LEE, JIN-HO;CHO, JAE-YONG;PARK, YOUNG-HOON |
分类号 |
C12N15/09;C12P13/08;C12N1/21;C12N9/88;C12N15/00;C12N15/11;C12N15/52;C12N15/70;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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