发明名称 ISOQUINOLINE ET BENZO[H]ISOQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF AS ANTAGONISTS OF HISTAMINE H3 RECEPTOR
摘要 The invention concerns a compound of formula (I) wherein (A) represents an unsaturated carbocycle with double bonds, I may represent a value from 0 to 4; m may represent a value from 0 to 3; n may represent a value from 0 to 6;-(C)I-,-(C)m-and-(C)n-represent, independently of one another, a-Cx-z-alkylidene group, optionally substituted by 1 to 4 substituents; R1 represents a hydrogen atom, a C1-C3 alkyl, a C1-C6 alkylcarbonyl, a C1-C6 alkoxycarbonyl group, R2 represents a hydrogen atom, an optionally substituted C1-C6 alkyl or C3-C6 cycloalkyl group. The invention is applicable in therapeutics, in the treatment of disorders improved by modulation of the histamine H3 receptor.
申请公布号 KR20080076910(A) 申请公布日期 2008.08.20
申请号 KR20087012407 申请日期 2006.11.22
申请人 SANOFI-AVENTIS 发明人 DIAZ MARTIN JUAN ANTONIO;ESCRIBANO ARENALES BEATRIZ;JIMENEZ BARGUENO MARIA DOLORES
分类号 C07D401/12;A61K31/4725;A61P25/00;C07D409/14 主分类号 C07D401/12
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