Organic compounds

摘要

The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene;;wherein X, Y, and R1 to R11 have the same meaning as given in the description.;Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.

主权项

1. A method of reducing the onset of skin irritation caused by either environmental stresses or by stresses caused by the application of chemical compounds to skin, by applying to the skin an effective amount of a topical skin care composition comprising both:
at least one (a) compound of the following formula wherein R is hydrogen or isopropyl; R1 is methyl or ethyl; and R2 is C1-C6 alkyl or C2-C6 alkenyl; or R1 and R2 together with the carbon atom to which they are attached form a C5 or C6 cycloalkyl ring; and the dotted line together with the carbon carbon bond represents a single bond or a double bond;
and,at least one (b) compound of the following formula wherein Y is a C4-C7 hydrocarbon residue, wherein the total amount of both compound (a) and compound (b) is at least 0.2% wt. of the total amount of the topical skin care composition.