ВАКЦИНА ПРОТИВ ВИРУСОВ ПАПИЛЛОМЫ ЧЕЛОВЕКА HPV16 ИHPV18 И ПО МЕНЬШЕЙ МЕРЕ ЕЩЕ ОДНОГО ТИПА HPV, ВЫБРАННОГО ИЗ HPV 31,45 ИЛИ 52

摘要

An immunogenic composition and methods for producing said composition, the composition comprising VLPs from HPV 16 and 18 and at least one other HPV cancer type, the other cancer type being selected from the list consisting of HPV types 31, 45 and 52, wherein the dose of the VLP of the at least one other cancer types is reduced relative to that of HPV 16 or 18.