COMPUESTOS DERIVADOS DE 5-BIFENIL-2-PIRROLIDONA; PROCESO DE PREPARACION DE DICHOS COMPUESTOS; COMPUESTOS INTERMEDIARIOS; PROCESO DE PREPARACION DE COMPUESTOS INTERMEDIARIOS, UTILES PARA PREPARAR UN INHIBIDOR DE LA ENDOPEPTIDASA NEUTRA.
摘要
<p>The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.</p>