发明名称 |
QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY |
摘要 |
The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors. |
申请公布号 |
US2008194578(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
US20070852604 |
申请日期 |
2007.09.10 |
申请人 |
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发明人 |
QIAN CHANGGENG;CAI XIONG;GOULD STEPHEN;ZHAI HAIXIAO |
分类号 |
A61K31/517;A61K31/497;A61P35/00;C07D239/94;C07D401/12;C07D403/12;C07D403/14;C07D405/12 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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